Effects of Permissive Hypercapnia on Pulmonary Mechanics and Hemodynamics during Mechanical Ventilation in Severe Acute Respiratory Distress Syndrome
نویسنده
چکیده
Alveolar atelectasis and low functional residual capacity are the hallmark of the patients with acute respiratory distress syndrome (ARDS) [1]. Lots of experiments have reported that large tidal volume (VT) and traditional VT (10 12 ml/kg) can induce lung injury. In order to minimize the risk of ventilator-induced lung injury (VILI), VT should be lowered during mechanical ventilation in ARDS [1,2]. This approach, known as controlled hypoventilation or permissive hypercapnia (PHC), has been associated with a decrease in mortality and fewer complications in patients with ARDS. But little is known about its consequences on hemodynamics and pulmonary mechanics in severe ARDS patients. In the present study, the effects of different VT on pulmonary mechanics and hemodynamic in patients with severe ARDS were inEffects of Permissive Hypercapnia on Pulmonary Mechanics and Hemodynamics during Mechanical Ventilation in Severe Acute Respiratory Distress Syndrome
منابع مشابه
هیپرکاپنی و هیپوکسمی اختیاری در نوزادان
Current, lung protection strategy possesses some degree of hypercapnia and hypoxia. Permissive hypercapnia and hypoxia may attenuate the complications of mechanical ventilation in neonates. Adapting this approach and thorough understanding of the biopathologic effects of hypercapnia and hypoxia could prevent mechano-trauma and air leak syndromes. This helps protecting the lung and inflammator...
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